LSU vs. Alabama: Week 11 Betting Preview and Odds from bet105

As Week 11 of the SEC season approaches, a classic rivalry is renewed as the LSU Tigers head to Tuscaloosa to take on the formidable No. 4 ranked Alabama Crimson Tide. This Saturday night showdown at Bryant-Denny Stadium is more than just a game; it’s a test of resilience for an LSU team in transition and a chance for Alabama to solidify its championship aspirations. For bettors, this high-stakes matchup offers a prime opportunity to get in on the action, and bet105 has all the odds you need.

A Tale of Two Programs

The LSU Tigers (5-3, 2-3 SEC) enter this game under a cloud of uncertainty. Following the recent dismissal of head coach Brian Kelly, the team is now led by interim coach Frank Wilson. In his first game at the helm, Wilson faces the monumental task of preparing his team for their toughest opponent of the season. “It’s a tremendous, humbling moment for myself,” Wilson stated, acknowledging the challenge ahead. “I will do my very best and die trying to represent us as a university, as a state, as a community, to the best of my ability, with dignity, honor, and pride.”

On the other side, the Alabama Crimson Tide (7-1, 5-0 SEC) are rolling. With an undefeated conference record, they are firmly in control of the SEC West and have their eyes on the College Football Playoff. A decisive victory over a rival would further strengthen their case as one of the nation’s elite teams.

Betting Odds and Analysis with bet105

This rivalry game presents a fascinating scenario for sports bettors. Let’s break down the key betting lines available at bet105.

Moneyline

The moneyline tells a clear story: Alabama is the heavy favorite at -408, meaning a $408 bet would be required to win $100. For those who believe in an upset, the Tigers present a tempting +307 underdog opportunity, where a $100 wager could yield a $307 profit. Given the turmoil in Baton Rouge and Alabama’s dominance, an LSU victory would be a significant upset.

Spread

The point spread is set at 10.5 points. This means that for a bet on Alabama to win, they must defeat LSU by 11 points or more. Conversely, a bet on LSU is a winner if they win the game outright or lose by 10 points or fewer. This is where the betting gets interesting. Can the Tigers, fueled by the emotion of a coaching change and the pride of a rivalry, keep the game closer than the experts think?

Total (Over/Under)

The game total is set at 50 points. Bettors must decide if the combined score of both teams will be over or under this number. Alabama’s potent offense will test a resilient LSU defense. The question is whether LSU’s offense can do enough to contribute to a high-scoring affair.

More Ways to Bet at bet105

bet105 offers a wide range of betting options beyond the main lines. You can find odds on first-half totals, and individual team point totals. For example, the over/under for LSU’s total points is set at 19.5, while Alabama’s first-half total is set at 30.5.

Game Information

• Matchup: LSU Tigers at Alabama Crimson Tide
• Kickoff Time: 6:30 p.m. CT
• Venue: Bryant-Denny Stadium – Tuscaloosa, Alabama
• TV Channel: ABC

Final Thoughts

This SEC West clash is packed with storylines. Will Alabama continue its march towards the playoffs, or will LSU rally under interim coach Frank Wilson to pull off a stunning upset? The betting odds at bet105 reflect the current state of these two programs, but in a rivalry game, anything can happen.

Head over to bet105 to check out the latest odds and place your bets on this and all the other exciting college football action.

Read our predictions for other notable games in Week 11 of NCAA Football;

Northwestern vs. USC – Friday, November 7:00p.m. ET
Oregon vs. Iowa – Saturday, November 8, 2025 at 3:30p.m. ET
Missouri vs. Texas A&M – Saturday, November 8, 2025 at 3:30p.m. ET