NBA Weekly Matchup Predictions – Back the Favorites or Bet on the Underdogs?

As the NBA regular season heats up, this week’s matchups are offering both exciting rivalries and prime betting opportunities. At bet105, we’ve broken down the latest predictions and percentages to help you make the most informed wagers. Here’s what to look for in these upcoming games.

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Cleveland Cavaliers (24%) vs. Indiana Pacers (76%)

The Cavaliers are heading into this game as major underdogs. With just a 24% chance of winning, Cleveland will need to bring a near-perfect performance to overcome Indiana’s dominant form. The Pacers, powered by consistent offense and depth off the bench, are the clear favorites here—and for good reason.

Prediction: Indiana Pacers to win

New York Knicks (35%) vs. Detroit Pistons (65%)

While the Knicks have shown flashes of brilliance this season, the Pistons are expected to outpace them with a 65% win probability. Detroit’s defensive pressure and rebounding advantage could be the deciding factors. Still, don’t count out a potential upset if New York’s perimeter shooting heats up early.

Prediction: Detroit Pistons to win, but consider a value bet on the Knicks if odds shift.

Atlanta Hawks (15%) vs. Brooklyn Nets (85%)

The Hawks are facing steep odds this week. With only a 15% chance of winning, they’ll need a breakout game from their stars to challenge a surging Brooklyn team. The Nets are executing well on both ends of the court and have the depth to manage any momentum the Hawks might build.

Prediction: Brooklyn Nets to win comfortably

New Orleans Pelicans (10%) vs. Milwaukee Bucks (90%)

This matchup is the biggest disparity of the week. The Bucks are heavy favorites at 90%, and it’s easy to see why. With MVP-caliber performances coming regularly from their stars, Milwaukee is likely to dominate unless the Pelicans can mount a miracle run.

Prediction: Milwaukee Bucks in a blowout

Minnesota Timberwolves (45%) vs. Memphis Grizzlies (55%)

This is the closest matchup of the week, and it could go either way. Memphis holds a slight edge at 55%, but Minnesota’s recent improvements and strong interior game make this a true toss-up. Expect a high-energy battle that may come down to the final possession.

Prediction: Slight lean toward Memphis Grizzlies, but a live bet might offer better timing.

Ready to turn predictions into profit? Head over to bet105’s betting homepage to place your bets on this week’s NBA action. With expert insights and competitive odds, there’s never been a better time to get in the game.