Oklahoma vs. Alabama: College Football Week 12 Betting Preview & Prediction
A marquee matchup in Week 12 of the college football season sees the Oklahoma Sooners travel to Tuscaloosa to
A marquee matchup in Week 12 of the college football season sees the Oklahoma Sooners travel to Tuscaloosa to take on the formidable Alabama Crimson Tide. This game carries significant weight for both teams, with Alabama looking to continue its dominant run and Oklahoma fighting to stay in the playoff conversation. This comprehensive betting preview from bet105 breaks down the odds, analyzes the teams, and provides an expert prediction for this highly anticipated SEC clash.
Oklahoma vs. Alabama Odds at bet105
At bet105, we provide the most competitive odds for all your college football betting needs. Here’s a look at the current lines for the Oklahoma vs. Alabama showdown:
| Bet Type | Oklahoma | Alabama |
|---|---|---|
| Spread | +6.5 | -6.5 |
| Moneyline | +180 | -218 |
| Total | O 46 | U 46 |
Odds are subject to change. For the latest odds, please visit bet105.
Alabama’s Resurgence and Offensive Firepower
After an early-season loss to Florida State, many were quick to write off the Crimson Tide. However, Alabama has silenced the doubters by rattling off seven consecutive victories, re-establishing themselves as a national title contender. The offense, led by quarterback Ty Simpson, has been particularly impressive, averaging 32.8 points per game and ranking fourth in the nation in offensive EPA per play. Simpson has been a model of efficiency, throwing for over 2,400 yards with an incredible 21-to-1 touchdown-to-interception ratio. While the passing attack soars, the run game has been a surprising area of weakness, ranking 128th in rush success rate. This could be a key factor against a stout Oklahoma run defense.
Oklahoma’s Defensive Prowess and Offensive Struggles
The Oklahoma Sooners enter this contest with a 7-2 record, largely thanks to a dominant defense. Brent Venables’ unit ranks first in the country in defensive success rate and allows a mere 15.5 points per game, good for eighth-best nationally. The Sooners have been especially effective against the run, ranking first in run success rate allowed. This strength will be crucial in containing Alabama’s offense. However, the Sooners’ offense has been a different story. Quarterback John Mateer has struggled since returning from a hand injury, averaging just 183.5 passing yards per game with more interceptions (4) than touchdowns (2) over his last four starts. The offense’s inability to consistently produce points puts immense pressure on the defense to be nearly perfect.
Key Matchup to Watch: Ty Simpson vs. Oklahoma’s Secondary
The outcome of this game could very well hinge on the performance of Alabama quarterback Ty Simpson against the Oklahoma secondary. Simpson has been playing at an elite level, demonstrating poise and accuracy that has him in the Heisman Trophy conversation. He faces a tough test against a Sooners defense that ranks 25th in EPA per pass allowed. However, Simpson has consistently shown the ability to dissect even the most complex defensive schemes. If Oklahoma’s defense can’t find a way to disrupt his rhythm, it could be a long day for the Sooners.
Prediction and Best Bet
While Oklahoma’s defense is formidable, their anemic offense is a major cause for concern, especially in a hostile environment like Bryant-Denny Stadium. John Mateer’s recent struggles suggest the Sooners will have a difficult time keeping pace with Alabama’s high-powered offense. Alabama has a clear advantage at the most important position on the field, and that should be the deciding factor.
We expect a competitive game in the first half, but Alabama’s talent and home-field advantage should allow them to pull away in the second half and win by at least a touchdown. Therefore, our best bet is to lay the points with the Crimson Tide.
Best Bet at bet105: Alabama -6.5
Oklahoma vs. Alabama FAQ
What is the spread for the Oklahoma vs. Alabama game? At bet105, the spread is currently set at Alabama -6.5.
Who is favored to win, Oklahoma or Alabama? Alabama is the favorite to win, with a moneyline of -218 at bet105. ESPN’s Football Power Index also gives Alabama a 71.6% chance of winning.
Where is the Oklahoma vs. Alabama game being played? The game will be played at Bryant-Denny Stadium in Tuscaloosa, Alabama.
What time is the Oklahoma vs. Alabama game? Kickoff is scheduled for 3:30 p.m. ET on Saturday, November 15, 2025.
What channel is the Oklahoma vs. Alabama game on? You can watch the game on ABC.
Conclusion
The Oklahoma vs. Alabama matchup promises to be a compelling contest between a dominant defense and a high-powered offense. While the Sooners have the defensive capabilities to slow down most opponents, the combination of Ty Simpson’s exceptional play and the hostile environment in Tuscaloosa should prove too much for an Oklahoma offense that has struggled to find consistency. For bettors looking to capitalize on this game, Alabama covering the spread at bet105 represents solid value.
Read our predictions for other notable games in Week 12 of NCAA Football;
Clemson vs. Louisville – Fri. Nov. 14 at 7:30pm ET
Minnesota vs. Oregon – Fri. Nov. 14 at 9:00pm ET
Notre Dame vs. Pittsburgh – Sat. Nov. 15 at 12:00pm ET
Texas vs. Georgia – Sat. Nov. 15 at 7:30pm ET
Remember to bet responsibly and always gamble within your means. For the latest odds and betting options on all college football games, visit bet105 today.
