Ravens vs. Bills Prediction, Odds & Best Bets: NFL Week 1
The Baltimore Ravens and Buffalo Bills clash in a highly anticipated Week 1 matchup to kick off their 2025

The Baltimore Ravens and Buffalo Bills clash in a highly anticipated Week 1 matchup to kick off their 2025 NFL season. This game features two of the league’s most dynamic quarterbacks, Lamar Jackson and Josh Allen, and is expected to be a close contest. The Ravens are slight favorites on the moneyline at bet105, making this an exciting game for bettors.
Ravens vs. Bills Odds
Here are the current odds from bet105 for the Ravens vs. Bills game:
Team | Spread | Moneyline | Total |
---|---|---|---|
Baltimore Ravens | -1 (-107) | -115 | Over 50.5 (-108) |
Buffalo Bills | +1 (-103) | +105 | Under 50.5 (-104) |
Odds are subject to change. Visit bet105 for the latest odds.
Ravens vs. Bills Prediction
This game is expected to be a tight contest, with the Ravens holding a slight edge. Based on our analysis of team performance, player matchups, and recent trends, we predict the Baltimore Ravens will win this game. The Ravens have a strong offense led by Lamar Jackson and the addition of Derrick Henry in the backfield gives them a powerful rushing attack. The majority of experts are also siding with the Ravens, with five out of six experts at USA Today picking them to win.
Ravens vs. Bills Spread Prediction
With the spread set at Ravens -1, this is essentially a pick’em. However, given the Ravens’ potent offense and the questions surrounding the Bills’ secondary, we believe the Ravens will cover the spread. Lamar Jackson’s dual-threat ability and the Ravens’ strong running game should be enough to give them the edge.
Best Player Prop Bets for Ravens vs. Bills
Here are some of the best player prop bets for the Ravens vs. Bills game, based on player performance and historical trends:
Lamar Jackson – Passing Touchdowns
Lamar Jackson has been a touchdown machine, and with the Bills’ secondary showing some vulnerability, the over on his passing touchdowns is an attractive bet. Jackson threw for 41 touchdowns last season and will be looking to start the 2025 season strong.
Josh Allen – Rushing Yards
Josh Allen is always a threat on the ground, but the Ravens have a defense that is athletic and capable of containing mobile quarterbacks. The under on his rushing yards could be a good value bet, especially if the Ravens’ defensive line can generate pressure.
Derrick Henry – Rushing Yards
Derrick Henry has a history of success against the Bills, and the Ravens are expected to rely on their running game. The over on his rushing yards is a solid bet, as he will likely see a heavy workload in his Ravens debut.
First Touchdown Scorer
For a higher-risk, higher-reward bet, consider the first touchdown scorer. Derrick Henry is a strong candidate given his red zone prowess. Josh Allen is also a good option due to his ability to run the ball in for a score.
Ravens and Bills Team Totals
Bet105 offers team total bets for both the Ravens and the Bills:
- Baltimore Ravens: Over 26.5 (-102) / Under 26.5 (-115)
- Buffalo Bills: Over 27.5 (+139) / Under 27.5 (-165)
Given the Ravens’ offensive firepower, the over on their team total is a strong possibility. The Bills’ total is a bit more of a toss-up, but the under could be a good play if the Ravens’ defense can control the game.
Final Thoughts
This Week 1 matchup between the Ravens and Bills has all the makings of a classic. With two of the league’s best quarterbacks and two of the top teams in the AFC, it’s a game you won’t want to miss. For bettors, there are plenty of opportunities to get in on the action at bet105. Be sure to check the latest odds and get your bets in before kickoff!