USC vs. Northwestern: College Football Betting Odds and Prediction
The No. 20 USC Trojans are set to face the Northwestern Wildcats in a Big Ten matchup with significant
The No. 20 USC Trojans are set to face the Northwestern Wildcats in a Big Ten matchup with significant College Football Playoff implications. This article provides a comprehensive analysis of the upcoming game, a breakdown of the latest betting odds from bet105, and a prediction for the final score.
Team Analysis: Trojans and Wildcats
The USC Trojans have had a strong season, boasting a 6-2 record and an undefeated 4-0 streak at home. Their recent 21-17 victory over Nebraska showcased a formidable defense, which will be a key factor in their game against Northwestern. With three of their four remaining games at home, the Trojans are in a favorable position to secure a spot in the College Football Playoff. However, they face a tough road game against the No. 6 Oregon Ducks, a team they lost to in their last encounter in 2023.
Northwestern comes into this game with a 5-3 record and a 3-2 standing in the Big Ten conference. They are looking to bounce back from a 28-21 loss to Nebraska and will have had a bye week to prepare for this crucial matchup. The Wildcats will need to bring their A-game to overcome the Trojans’ home-field advantage and strong defensive line.
Betting Odds Breakdown
Here are the latest betting odds for the USC vs. Northwestern game, courtesy of bet105:
| Bet Type | Northwestern | USC |
|---|---|---|
| Moneyline | +430 | -627 |
| Spread | +14.5 (-114) | -14.5 (-102) |
| Total (Over/Under) | Over 53 (-101) | Under 53 (-118) |
The betting lines from bet105 show a significant point spread, with USC favored to win by 14.5 points. The moneyline odds also reflect this, with USC at -627 and Northwestern at +430. The over/under for the game is set at 53 points, suggesting a moderately high-scoring affair.
Betting Insights and Prediction
The large point spread is likely due to USC’s strong home record and Northwestern’s recent loss. However, the Wildcats have had extra time to prepare for this game, which could give them an edge. The over/under of 53 points is an interesting line, as both teams have been involved in relatively low-scoring games recently.
While USC is the clear favorite, Northwestern has the potential to cover the spread. The key to this game will be whether the Wildcats’ offense can find a way to score against the Trojans’ stout defense. Ultimately, we predict that USC will win the game, but Northwestern will keep it closer than the spread suggests.
Prediction: USC 31, Northwestern 20
Conclusion
The USC vs. Northwestern game is shaping up to be an exciting matchup with significant implications for the College Football Playoff. The betting odds from bet105 favor the Trojans, but the Wildcats have the potential to pull off an upset. Be sure to check out bet105 for the latest odds and to place your bets on this and other college football games.
Oregon vs. Iowa – Saturday, November 8, 2025 at 3:30p.m. ET
Missouri vs. Texas A&M – Saturday, November 8, 2025 at 3:30p.m. ET
LSU vs Alabama – Saturday, November 8, 2025 at 7:30p.m. ET
